Cefazolin
Trade name: Ancef, Kefzol
Class: Antibiotic "cephalosporines" FIRST GENERATION
Pregnancy: (Category B)
Action: Bind to bacterial cell wall membrane, causing cell death
Uses
Treatment of:
Skin and skin structure infections (including burn wounds)
Pneumonia
Otitis media
Urinary tract infections
Bone and joint infections
Septicemia (including endocarditic) caused by susceptible organisms
Perioperative prophylaxis
Dose
By intramuscular injection or intravenous injection or infusion, 05–1 g every 6–12 hours; CHILD, 25–50 mg/kg daily (in divided doses), increased to 100 mg/kg daily in severe infections
Contraindications
Hypersensitivity to cephalosporin or Penicillin, renal failure, Pregnancy, Lactation
Side effects
Nausea, vomiting, diarrhea, anorexia, abdominal pain, flatulence, skin rashes super-infection, heartburn, sore mouth, bone marrow depression: (Decrease WBC, decreased platelets, decreased Hct Nephrotoxicity, (pain, abscess at injection site, phlebitis and inflammation at IV site
Nursing considerations
Infuse over 30 minutes unless otherwise indicated
Therapy should be continued for at least 2-3 days after symptoms of infection have disappeared
Assess client with a history of hypersensitivity reaction “for penicillin or cephalosporin”
Assess client financial status These drugs are usually expensive
If GI upset occurs administer Drugs with meals “Should be administered on empty stomach”
Obtain liver & renal studies
الأحد أبريل 22, 2012 6:17 pm