METHYLDOPA. Trade name: Aldomine +IKACOR

METHYLDOPA:
Trade name: Aldomine.
Classification: antihypertensive, centrally acting antiadrenergic agent.
Action:
1. The active metabolite alphamethylenorepinephrin.
2. Lowering B.P by stimulating central inhibitory alpha-adrenergic receptors.
Uses:
H.T.N and H.T.N crises (parental).
Contraindication:
1) Hypersensitivity. 2) Active hepatic diseases. 3) Pregnancy. 4) Phenochromocytoma.
Side effects:
Headache, dizziness, weakness, bradycardia, orthostatic hypertension, dry mouth, N & V, hemolytic anemia, jaundice, leukopnea and male impotence.
Dosage:
Tabs: initially 250 mg bidortid.
Nursing considerations:
1. Avoid activities that need mental awareness such as driving.
2. Note any evidence of jaundice and liver function test.
3. Advise pt to rise from bed slowly.
4. Explain for pt the urine maybe change to dark-blue color.
5. Advise client to carry a card detailing current medication regimens always.

IKACOR:
Verapamil hydrochloride 40-80-120 mg.
Action:
Ca channel blockers.
Indication:
1) Antianginal. 2) Antirrhythemic. 3) H.T.N.
Contraindication:
1) Sever left ventricular dysfunction. 2) Hypotension.
3) Sick sinus syndrome except pt use base maker.
Side effects:
C.V.S: hypotension – bradycardia – C.H.F.
C.N.S: dizziness – headache – fating.
G.I.T: constipation – nausea.
Overdose:
Use supportive B-adrenergic stimulation or parental administration of Ca solution.